M. Diac, C. Lucasievici, N. Girlescu, G. Toma, A. Knieling, S. Damian, D. B. Iliescu
Abstract: Ankylosing spondylitis (AS) is a chronic inflammation with a wide clinical spectrum of articular and extra-articular changes that occurs in genetically predisposed individuals and is triggered by environmental factors. Cardiovascular involvement in HLA-27 positive spondyloarthropathies has been demonstrated by multiple working groups. All studies share findings that include conduction abnormalities and aortic root pathologies (aortitis-type) as well as aortic valve disease (1-4). Several authors (5-10) have highlighted pathological similarities between AS and Marfan syndrome (MS), suggesting that there may be a common tissue susceptibility factor.
We present the case of a patient with AS who suffered a spinal cord injury and a two-stage bleeding aortic dissection. Keywords: aortic dissection, ankylopoietic spondylitis, aortitis, collagenosis.
 is a chronic inflammation with a wide clinical spectrum of articular and extra-articular changes that occurs in genetically predisposed individuals and is triggered by environmental factors. Cardiovascular involvement in HLA-27 positive spondyloarthropathies has been demonstrated by multiple working groups. All studies share findings that include conduction abnormalities and aortic root pathologies (aortitis-type) as well as aortic valve disease (1-4). Several authors (5-10) have highlighted pathological similarities between AS and Marfan syndrome (MS), suggesting that there may be a common tissue susceptibility factor.
<br /> We present the case of a patient with AS who suffered a spinal cord injury and a two-stage bleeding aortic dissection.&redirect_uri=http://rjlm.ro/index.php/arhiv/1028)